Which of the following is true of the binding energy derived from enzyme-substrate interactions?
A)It cannot provide enough energy to explain the large rate accelerations brought about by enzymes.
B)It is sometimes used to hold two substrates in the optimal orientation for reaction.
C)It is the result of covalent bonds formed between enzyme and substrate.
D)Most of it is derived from covalent bonds between enzyme and substrate.
E)Most of it is used up simply binding the substrate to the enzyme.

Question

Quizplus · Accepted Answer

The binding energy derived from enzyme-substrate interactions is sometimes used to hold two substrates in the optimal orientation for reaction, as seen in some enzyme-catalyzed reactions. This binding energy can also contribute to the rate acceleration observed in enzyme-catalyzed reactions, although it is not the only factor involved. It is not the result of covalent bonds formed between enzyme and substrate, as these interactions are typically weaker than covalent bonds. Most of the binding energy is not used up simply binding the substrate to the enzyme, as the actual chemical reaction requires additional energy input.

Which of the Following Is True of the Binding Energy