Cyanide,oligomycin,and 2,4-Dinitrophenol (DNP)are Inhibitors of Mitochondrial Aerobic Phosphorylation
Cyanide,oligomycin,and 2,4-dinitrophenol (DNP) are inhibitors of mitochondrial aerobic phosphorylation.Which of the following statements correctly describes the mode of action of the three inhibitors?
A) Cyanide and 2,4-dinitrophenol inhibit the respiratory chain,and oligomycin inhibits the synthesis of ATP.
B) Cyanide inhibits the respiratory chain,whereas oligomycin and 2,4-dinitrophenol inhibit the synthesis of ATP.
C) Cyanide,oligomycin,and 2,4-dinitrophenol compete with O2 for cytochrome oxidase (complex IV) .
D) Oligomycin and cyanide inhibit synthesis of ATP;2,4-dinitrophenol inhibits the respiratory chain.
E) Oligomycin inhibits the respiratory chain,whereas cyanide and 2,4-dinitrophenol prevent the synthesis of ATP.
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