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People Who Are Heterozygous for HLA-DQ2 and HLA-DQ8 Allotypes Are

Question 26

Essay

People who are heterozygous for HLA-DQ2 and HLA-DQ8 allotypes are at greater risk of developing type 1 diabetes than those who are homozygous for HLA-DQ2 or HLA-DQ8.
A.Explain the reason for this increased susceptibility.
B.Why is the above statement true mainly for people of northern European origin but not for some other ethnic groups?

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A.Increased risk of developing type 1 di...

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