_____ results from alloreactions mediated by donor T cells in the graft subsequent to hematopoietic stem-cell transplantation.

Question

Quizplus · Accepted Answer

Graft-versus-host disease (GVHD) is a common complication of hematopoietic stem-cell transplantation, in which the donor T cells in the graft recognize the recipient's tissues as foreign and mount an immune response against them. This can lead to tissue damage and various clinical manifestations, ranging from skin rashes to life-threatening organ dysfunction. Acute and chronic rejection are types of rejection that occur when the recipient's immune system mounts an attack against the transplanted organ or tissue. Serum sickness is a type of immune-mediated reaction that results from the formation of immune complexes, while hyperacute rejection is a rare and rapid rejection that occurs due to pre-existing antibodies against the transplant.

_____ Results from Alloreactions Mediated by Donor T Cells in the Graft