_____ accounts for the production of different isoforms of the CD45 protein observed in naive,effector,and memory T cells.

Question

Quizplus · Accepted Answer

Alternative splicing is the process by which different combinations of exons within a gene can be spliced together to create different isoforms of the mRNA and protein product. This is the most likely explanation for the differences in CD45 isoforms observed in different T cell populations. Isotype switching, affinity maturation, somatic hypermutation, and recirculation to peripheral tissues are not relevant to the production of different CD45 isoforms.

_____ Accounts for the Production of Different Isoforms of the CD45