A distinguishing feature of FcγRIIB1 compared with FcγRIIA is _____.

Name: A distinguishing feature of FcγRIIB1 compared with FcγRIIA is _____.
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Question

Quizplus · Accepted Answer

FcγRIIB1 has ITIMs (immunoreceptor tyrosine-based inhibitory motifs) in its cytoplasmic tails, which leads to its inhibitory function. FcγRIIA, on the other hand, activates cells and induces endocytosis, and does not possess ITIMs. The ability to bind to IgG1 or expression on NK cells are not defining features that distinguish FcγRIIB1 from FcγRIIA.

A Distinguishing Feature of FcγRIIB1 Compared with FcγRIIA Is _____