The Release of Lytic Granules from Cytotoxic T Cells Is

The release of lytic granules from cytotoxic T cells is aimed specifically at infected target cells while preserving the integrity of neighboring,uninfected cells.This is best explained by the observation that _____.

A) only target cells bearing appropriate peptide:MHC class I complexes are susceptible to necrosis
B) redistribution of lytic granules in the T cell delivers them to confined areas on the target cell in contact with the T cell
C) regulatory T cells deliver survival signals to uninfected neighboring cells that renders them resistant to cytotoxins
D) the amount of cytotoxins in a given cytotoxic T cell is so limited that only the cell closest to the T cell will succumb to the effects of perforin and granzyme
E) uninfected cells are highly resistant to the effects of cytotoxins.