Which of the following cell-surface glycoproteins is characteristic of stem cells,but stops being expressed when a cell has committed to the T-cell developmental pathway?

Question

Quizplus · Accepted Answer

CD34 is a cell-surface glycoprotein which is commonly found on stem cells, but stops being expressed when a cell has committed to a specific developmental pathway. T-cell precursors express CD34, but once they have committed to the T-cell pathway they lose CD34 expression. CD2, CD3, and CD25 are all cell-surface glycoproteins associated with T cells, but they are not specific to stem cells and do not change expression upon commitment to a developmental pathway. MHC class II is a cell-surface glycoprotein involved in antigen presentation and is not specific to stem cells or T cell development.

Which of the Following Cell-Surface Glycoproteins Is Characteristic of Stem