_______ of thymocytes is necessary to produce a T-cell repertoire capable of interacting with self-MHC molecules.

Question

Quizplus · Accepted Answer

Positive selection is necessary for thymocytes to be able to recognize and interact with self-MHC molecules, which is essential for the generation of a functional T-cell repertoire. This process allows for the survival and maturation of thymocytes that are capable of recognizing self-MHC molecules, while those that cannot are eliminated through apoptosis or negative selection. Receptor editing and isotype switching are not involved in T-cell development.

_______ of Thymocytes Is Necessary to Produce a T-Cell Repertoire