If the Process of Positive Selection Did Not Occur,then

If the process of positive selection did not occur,then

A) a condition resembling immune dysregulation,polyendocrinopathy,enteropathy,X-linked syndrome (IPEX) would develop
B) a condition resembling autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) would develop
C) naive T cells would be unable to undergo differentiation in secondary lymphoid tissues
D) malignant transformation would be more likely because of the accumulation of multiple mutations
E) only a very small percentage of circulating T lymphocytes would be able to become activated.