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In Reference to the Interaction Between T-Cell Receptors and Their

Question 43

Multiple Choice

In reference to the interaction between T-cell receptors and their corresponding ligands,which of the following statements is correct?

A) The organization of the T-cell receptor antigen-binding site is distinct from the antigen-binding site of immunoglobulins.
B) The orientation between T-cell receptors and MHC class I molecules is different from that of MHC class II molecules.
C) The CDR3 loops of the T-cell receptor α and β chains form the periphery of the binding site making contact with the α helices of the MHC molecule.
D) The most variable part of the T-cell receptor is composed of the CD3 loops of both the α and β chains.
E) All of the above statements are correct.

Correct Answer: