Directional selection is best described as
A) all polymorphic alleles preserved in a population
B) T-cell receptor interaction with peptide:MHC complexes directed to a planar interface
C) a mechanism in T cells that is analogous to affinity maturation of immunoglobulins
D) selected alleles increase in frequency in a population
E) selection of most appropriate transplant donor directed at the identification of identical or similar combinations of HLA alleles compared with the transplant recipient.
Correct Answer:
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Q43: In reference to the interaction between T-cell
Q44: T-cell receptors interact not only with peptide
Q45: Describe (A)five ways in which T-cell receptors
Q46: All of the following are highly polymorphic
Q47: To which domain of MHC class I
Q49: The_ refers to the complete set of
Q50: The combination of all HLA class I
Q51: The peptide-binding groove of MHC class I
Q52: The CDR3 loops of the T-cell receptor
Q53: the following HLA α-chain loci,which one exhibits
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