Which of the following removes CLIP from MHC class II molecules?

Question

Quizplus · Accepted Answer

HLA-DM is the chaperone molecule that catalyzes the displacement of CLIP from the peptide-binding groove of MHC class II molecules, allowing other antigens to be presented. HLA-DO, on the other hand, acts as an inhibitor of HLA-DM and can prevent the removal of CLIP in certain contexts. HLA-DP, HLA-DQ, and HLA-DR are all different alleles of MHC class II molecules and are not directly involved in the removal of CLIP.

Which of the Following Removes CLIP from MHC Class II