Identify the correct order of gene segments in a rearranged heavy-chain gene in a naive B cell.

Question

Quizplus · Accepted Answer

The correct order of gene segments in a rearranged heavy-chain gene in a naive B cell is Leader (L) segment, Variable (V), Diversity (D), and Joining (J) segments (collectively VDJ), followed by constant (C) region segments for different isotypes (μ, δ, etc.), with switch (S) regions and other regulatory elements (U, B) involved in class switch recombination. Option A correctly reflects this organization.

Identify the Correct Order of Gene Segments in a Rearranged