Early mapping of the HD gene was done using _______.

Question

Quizplus · Accepted Answer

RFLP mapping, or Restriction Fragment Length Polymorphism mapping, was a commonly used technique in the 1990s to map the location of genes on chromosomes. It involves cutting DNA samples with restriction enzymes and then sorting the resulting fragments by size using gel electrophoresis. The size differences can reveal differences between individuals or strains, allowing for the discovery of polymorphisms that can be used to map disease genes. RFLP mapping was one of the early techniques used to map the location of the HD gene on chromosome 4.

Early Mapping of the HD Gene Was Done Using _______