Which of the following is true about histone acetyltransferase HAT ?
A)HATs have an overall effect of increasing the positive charges on DNA.
B)HATs will make the chromatin more compacted and less available to transcription regulatory proteins.
C)HATs will remove acetyl groups from histone proteins.
D)HATs are usually linked to increasing gene expression.
E)HATs will add acetyl groups to DNA.

Question

Quizplus · Accepted Answer

HATs are enzymes that add acetyl groups to histone proteins. This post-translational modification (PTM) neutralizes the positive charges on the histones and allows DNA to become more accessible to transcriptional regulatory proteins. Therefore, HATs are typically linked to increasing gene expression rather than making chromatin more compacted.

Which of the Following Is True About Histone Acetyltransferase HAT