The ENCODE Project's goal was to identify all functional DNA sequences within the human genome.Which of the following is a finding from ENCODE?
A)ENCODE determined that approximately 25% of the human genome has some sort of biochemical function.
B)ENCODE determined that approximately 15% of the human genome codes for a protein.
C)ENCODE was able to classify that a large part of the human genome is "Junk DNA."
D)ENCODE was able to determine that each enhancer exerts its regulatory function on only a single gene.
E)ENCODE was able to determine that 75% of the genome is transcribed in at least one cell type.

Question

Quizplus · Accepted Answer

One key finding of the ENCODE project was that 75% of the genome is transcribed in at least one cell type, indicating that much of the genome is functional in some way. Option A is close but not quite accurate, as ENCODE did not necessarily identify all functional DNA sequences, but rather showed that much of the genome has some sort of biochemical activity. Option B is incorrect, as only a small proportion of the genome actually codes for proteins. Option C is also incorrect, as the concept of "junk DNA" has largely been debunked in light of ENCODE and other genomic studies. Option D is also incorrect, as enhancers can regulate multiple genes.

The ENCODE Project's Goal Was to Identify All Functional DNA