What is responsible for initiating the inflammatory response in addition to immunoglobulin E (IgE)?

Question

Quizplus · Accepted Answer

Basophils, a type of white blood cell, play a role in initiating the inflammatory response through the release of histamine and other chemical mediators. IgE can also initiate the inflammatory response through its binding to mast cells, which also release histamine and other mediators. Eosinophils, lymphocytes, and neutrophils may contribute to the inflammatory response but are not primarily responsible for initiating it.

What Is Responsible for Initiating the Inflammatory Response in Addition