Cystic fibrosis is caused by the allele f, which is completely recessive to the normal dominant allele F. Consider a couple with the genotype Ff. What is the chance that their first child will develop cystic fibrosis?

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With the genotype Ff, the couple is heterozygous, meaning they carry one copy of the recessive allele f. The chance of passing on this allele to their child is 50%. Therefore, there is a 25% chance that their first child will inherit two copies of the recessive allele f and develop cystic fibrosis.

Cystic Fibrosis Is Caused by the Allele F, Which Is