The outbreak of a disease, such as the bubonic plague, that kills large numbers of people in a city is an example of

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A disease outbreak that kills large numbers of people is an example of a density-dependent factor because the impact of the disease is directly proportional to the density or population size of the affected area. The disease spreads more quickly and easily in areas with high population densities, causing higher rates of infection and death.

The Outbreak of a Disease, Such as the Bubonic Plague