Which two CD markers are helpful in differentially identifying CLL from hairy cell leukemia?
A) CD19 and CD5
B) CD5 and CD11c
C) CD5 and CD10
D) sIg and CD25

Question

Quizplus · Accepted Answer

CD5 and CD11c are helpful in differentially identifying CLL from hairy cell leukemia. CLL typically expresses CD5 and weak CD11c, while hairy cell leukemia typically expresses CD11c strongly and is negative for CD5. The other options are not as specific for differentiating between CLL and hairy cell leukemia. CD19 and CD5 are commonly expressed in both CLL and hairy cell leukemia, and CD10 is typically negative in both. sIg and CD25 are not consistently expressed in either disease.

Which Two CD Markers Are Helpful in Differentially Identifying CLL