A blood sample from a patient suspected of having ALL is received in the flow lab for immunophenotyping. The analysis is performed, and standard B-cell markers are present, but the patient is also CD33-positive. What is the most likely reason for this occurrence?
A) The patient has a poorer prognosis than standard ALL.
B) The patient is responding to the chemotherapy.
C) The patient has ALL with aberrant myeloid cellular antigens.
D) It cannot be determined by the information given.

Question

Quizplus · Accepted Answer

The presence of CD33 in addition to standard B-cell markers indicates the patient has ALL with aberrant myeloid cellular antigens. This may affect prognosis and treatment options.

A Blood Sample from a Patient Suspected of Having ALL