A Patient Has Been Diagnosed with a Coagulopathy and Has

A patient has been diagnosed with a coagulopathy and has been given Coumadin as a mode of treatment. What screening test(s) should be performed to monitor this treatment, and what effect will this therapy have on the coagulation pathway?

A) APTT; initial decrease in the vitamin K-dependent factors of the intrinsic pathway
B) PT-INR; initial decrease in the vitamin K-dependent factors of the extrinsic pathway
C) PT-INR and APTT; initial decrease in the vitamin K-dependent factors of all pathways
D) PT-INR; initial decrease in all vitamin K-dependent serine proteases