A patient being treated with heparin therapy has a 65% decrease in platelet count from the baseline count after 6 days of being on the anticoagulant. What is the probable cause of the decrease?

Question

Quizplus · Accepted Answer

A decrease in platelet count from baseline after being on heparin therapy for 5-10 days is likely caused by heparin-induced thrombocytopenia (HIT), a condition in which the body produces antibodies against platelet factor 4-heparin complexes leading to increased platelet consumption and decreased platelet count. DIC (disseminated intravascular coagulation), TTP (thrombotic thrombocytopenic purpura), and APLS (antiphospholipid syndrome) can also cause thrombocytopenia, but HIT is the most likely cause given the scenario provided.

A Patient Being Treated with Heparin Therapy Has a 65