In PNH, cells are susceptible to complement-induced lysis. This is thought to result from the lack of what two regulating factors?
A) LCAT and lipoprotein
B) DAF and MIRL
C) HDL and VLDL
D) Beta and alpha lipoprotein

Question

Quizplus · Accepted Answer

In PNH, cells are susceptible to complement-induced lysis due to the lack of two regulating factors: decay-accelerating factor (DAF) and membrane inhibitor of reactive lysis (MIRL). LCAT, lipoprotein, HDL, VLDL, beta, and alpha lipoprotein are not directly related to complement regulation in PNH.

In PNH, Cells Are Susceptible to Complement-Induced Lysis