The Wittig reaction favours cis stereochemistry of the resultant alkene product.

Question

Quizplus · Accepted Answer

The Wittig reaction leads to the formation of a double bond between the carbonyl carbon and the β-carbon of the ylide. The geometry of the double bond is determined by the relative stereochemistry of the reacting groups. The reaction typically favors the cis stereochemistry of the resulting alkene product. However, trans products can also be formed if the reactants are appropriately designed.

The Wittig Reaction Favours Cis Stereochemistry of the Resultant Alkene