The Grignard reagent is an example of an umpolung nucleophile.

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The Grignard reagent is an example of an umpolung nucleophile because it adds to the carbonyl carbon of aldehydes and ketones in a nucleophilic addition reaction through a polarized mechanism that involves the formation of a new carbon-carbon bond and the inversion of polarity at the carbon center. This reaction transforms a carbonyl compound into an alcohol, which is a higher polarity functional group.

The Grignard Reagent Is an Example of an Umpolung Nucleophile