The sequencing method that cuts the DNA of an entire chromosome into small fragments and then clones these fragments is called
A)shotgun sequencing.
B)clone-by-clone sequencing.
C)RFLP sequencing.
D)consensus sequencing.

Question

Quizplus · Accepted Answer

Shotgun sequencing is the method of choice for sequencing entire genomes, including chromosomes. This process involves randomly breaking the DNA into small fragments and then cloning and sequencing these fragments. The resulting sequence data is then assembled using computational tools to reconstruct the original chromosome sequence. This method has been used successfully to sequence the genomes of many organisms including humans, mice, and bacteria.

The Sequencing Method That Cuts the DNA of an Entire