A mutation that affects Ca⁺⁺ binding to calmodulin is most likely to interfere with what aspect of a signal transduction pathway? A)The flow of Ca⁺⁺ ions through ion channel receptors B)The cellular response to the second messenger C)The MAP kinase cascade D)G protein activity

Question

Quizplus · Accepted Answer

Ca⁺⁺ binding to calmodulin is a key step in the activation of enzymes and other cellular responses to second messengers. Therefore, a mutation that affects this binding is most likely to interfere with the cellular response to the second messenger, which is the function of this signal transduction pathway. The other options mentioned (ion channel receptors, MAP kinase cascade, and G protein activity) may be affected by other mutations, but not by one that specifically affects Ca⁺⁺ binding to calmodulin.

A Mutation That Affects Ca++ Binding to Calmodulin Is Most

A Mutation That Affects Ca⁺⁺ Binding to Calmodulin Is Most