People with Alzheimer's lose a sense of their relationship to the world during the mild stage,when the disease progresses into the temporal and frontal lobes.

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During the mild stage of Alzheimer's, individuals may experience impaired memory and cognitive function but generally retain a sense of their relationship to the world. As the disease progresses into the temporal and frontal lobes, more significant cognitive decline occurs, including difficulty with language, problem-solving, and behavior control, which can disrupt an individual's sense of self and relationship to the world.

People with Alzheimer's Lose a Sense of Their Relationship to the World