Fill in the missing blanks with single words.
In the recent past, virus vectors used in gene therapy trials were often based on a type of retrovirus called a ______1_______retrovirus. They had the advantage of allowing a _____2_____ DNA to be stably inserted into the _____3____ DNA of cells. For cells that are short-lived, such as blood cells, the hope was that a certain percentage of _____4_____ cells might be successfully transduced so that there was a self-renewing population of cells carrying the desired _____2_____ DNA. Unfortunately, vectors based on ______1_______retroviruses have a poor safety profile: there is little control over where they ______5_______ into the _____3____ DNA and sometimes when they _____5_____ they activate a neighboring _____6_____, causing _____7_____. As a result, in modern gene therapy trials it is now commonplace to use self-_____8______ strains of a class of retrovirus vectors known as _____9____ that are much safer to use.
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2. therapeutic.
3....
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