Which patient,when compared with the general population,would require a larger dose or more frequent administration of a drug to attain a therapeutic response?
A) A 29 year old who has been diagnosed with kidney failure
B) A 35-year-old obese male who is being evaluated for an exercise program
C) A 52 year old diagnosed with hypothyroidism and decreased metabolic rate
D) A 72 year old with decreased circulatory status

Question

Quizplus · Accepted Answer

Obese individuals often require larger or more frequent doses of drugs to achieve therapeutic effects due to their larger body mass and potentially different pharmacokinetics, such as altered distribution and metabolism of the drug.

Which Patient,when Compared with the General Population,would Require a Larger