An enzyme has a total of four active sites. When you denature the molecule and study its composition, you find that each active site occurs on a different polypeptide. Which of the following hypotheses does this observation support?
A) The enzyme requires a cofactor to function normally.
B) The protein's structure is affected by temperature and pH.
C) The enzyme is subject to allosteric regulation.
D) The protein has quaternary structure.

Question

Quizplus · Accepted Answer

The observation that each active site occurs on a different polypeptide supports the hypothesis that the protein has quaternary structure, which refers to the arrangement of multiple polypeptide chains that form a larger protein complex. Each polypeptide chain contributes to the formation of the active sites, indicating that they are working together as a single functional unit in the enzyme.

An Enzyme Has a Total of Four Active Sites