Steroid hormones bind to receptors inside the cell and alter their conformation. The hormone- receptor complex is then transported into the nucleus, where it can directly affect gene expression. To get from the location where the receptor binds the hormone to its site of action, the receptor- hormone complex must

Question

Quizplus · Accepted Answer

To affect gene expression, the hormone-receptor complex must enter the nucleus. The transport of molecules into the nucleus occurs through the nuclear pore complex. Therefore, the receptor-hormone complex must be transported through the nuclear pore complex to its site of action. Choices A and B are incorrect because steroid hormones and their receptors are already lipid soluble and do not require carrier molecules or entrance into the endoplasmic reticulum. Choice D is incorrect because the conformational change already occurred when the hormone bound to the receptor.

Steroid Hormones Bind to Receptors Inside the Cell and Alter