Pemphigus Vulgaris Is an Autoimmune Disorder in Which Antibodies Are

Pemphigus vulgaris is an autoimmune disorder in which antibodies are produced against the cadherins of desmosomes. The blistering seen in these individuals is probably a result of

A) loss of cell- cell adhesion.
B) inadequate production of cytoskeletal proteins.
C) a decrease in flexibility of the cell membrane.
D) inadequate numbers of G- protein receptors.