During periods of starvation,gluconeogenesis increases in the liver.Which of the following is a major substrate for glucose biosynthesis under these conditions?
A) glutamate
B) alanine
C) urea
D) fatty acids

Question

Quizplus · Accepted Answer

During periods of starvation, the body begins to break down muscle tissue to produce amino acids, primarily alanine. Alanine is then transported to the liver where it is converted to glucose through gluconeogenesis. Therefore, alanine is a major substrate for glucose biosynthesis during starvation. Glutamate and urea are not major substrates for gluconeogenesis, and fatty acids are mainly used for energy production in tissues such as muscle and adipose tissue.

During Periods of Starvation,gluconeogenesis Increases in the Liver