Which enzyme of the citrate cycle catalyzes the oxidative decarboxylation reaction that produces CO₂, NADH, and succinyl-CoA? A) "pyruvate dehydrogenase" B) "citrate synthase" C) "isocitrate dehydrogenase" D) "$\alpha$-ketoglutarate dehydrogenase"

Question

Quizplus · Accepted Answer

The enzyme that catalyzes the oxidative decarboxylation reaction that produces CO₂, NADH, and succinyl-CoA is the 2-ketoglutarate dehydrogenase complex, or simply "ketoglutarate dehydrogenase." Option A refers to the enzyme that transforms pyruvate into acetyl-CoA, option B refers to the enzyme that catalyzes the condensation of acetyl-CoA and oxaloacetate to produce citrate, and option C refers to the enzyme that catalyzes the conversion of isocitrate into alpha-ketoglutarate.

Which Enzyme of the Citrate Cycle Catalyzes the Oxidative Decarboxylation α\alphaα

Which Enzyme of the Citrate Cycle Catalyzes the Oxidative Decarboxylation $\alpha$