An in vitro study shows that $\alpha$-ketoglutarate dehydrogenase is inhibited in the citrate cycle. What is a possible explanation for this inhibition? A) high levels of ATP B) low levels of Ca²⁺ C) low levels of NADH D) high levels of ADP

Question

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High levels of ATP can inhibit the citrate cycle by feedback inhibition of key enzymes such as the F1F1F1S1F1F1F10-ketoglutarate dehydrogenase.

An in Vitro Study Shows That α\alphaα -Ketoglutarate Dehydrogenase Is Inhibited in the Citrate Cycle

An in Vitro Study Shows That $\alpha$ -Ketoglutarate Dehydrogenase Is Inhibited in the Citrate Cycle