Which scenario would allow $\beta$-arrestin to bind to the GPCR? A) "$\beta$ARK is internalized into the endosome." B) "The receptor is phosphorylated." C) "G _$\alpha$ is bound to GDP." D) "The regulatory subunit of $\beta$-arrestin is removed."

Question

Quizplus · Accepted Answer

F1F1F1S1F1F1F10-arrestin binds to GPCRs that have been phosphorylated by a GPCR kinase (GRK). Therefore, scenario B, in which the receptor is phosphorylated, would allow F1F1F1S1F1F1F10-arrestin to bind to the GPCR.

Which Scenario Would Allow β\betaβ -Arrestin to Bind to the GPCR? A)

Which Scenario Would Allow $\beta$ -Arrestin to Bind to the GPCR?
A)