Place the following steps in proper order:
A.phosphorylation of RTK cytoplasmic tails
B.activation of downstream signaling pathways
C.ligand binding,receptor dimerization,and kinase activation
D.protein binding to RTK phosphotyrosines and phosphorylation of target proteins
A) C, D, A, B
B) C, B, A, D
C) C, A, D, B
D) B, C, A, D

Question

Place the following steps in proper order: 
A.phosphorylation of RTK cytoplasmic tails
B.activation of downstream signaling pathways
C.ligand binding,receptor dimerization,and kinase activation
D.protein binding to RTK phosphotyrosines and phosphorylation of target proteins
A) C, D, A, B
B) C, B, A, D
C) C, A, D, B
D) B, C, A, D

Quizplus · Accepted Answer

The proper order of RTK activation is as follows: (C) ligand binding, receptor dimerization, and kinase activation; (A) phosphorylation of RTK cytoplasmic tails; (D) protein binding to RTK phosphotyrosines and phosphorylation of target proteins; (B) activation of downstream signaling pathways.

Place the Following Steps in Proper Order