Consider the following interaction between a protein and its ligand: [P] + [L] $\harr$ [PL]. Which equation describes the dissociation constant of this interaction?
A) [PL] / [P][L]
B) [P][L] / [PL]
C) [PL] / [P]
D) [PL][P] / [L]

Question

Consider the following interaction between a protein and its ligand: [P] + [L]     $\harr$ [PL]. Which equation describes the dissociation constant of this interaction?
A) [PL] / [P][L]
B) [P][L] / [PL]
C) [PL] / [P]
D) [PL][P] / [L]

Quizplus · Accepted Answer

The dissociation constant (Kd) for a protein-ligand interaction is defined as the ratio of the dissociated forms ([P][L]) to the associated form ([PL]). Therefore, the correct equation is Kd = [P][L] / [PL].

Consider the Following Interaction Between a Protein and Its Ligand ↔\harr↔

Consider the Following Interaction Between a Protein and Its Ligand $\harr$