Which of the following statements about the clamp-type chaperone protein Hsp70 is correct?
A) Hsp70 uses ATP binding and hydrolysis energy to assist in the folding of a protein.
B) Hsp70 is a multi-subunit protein shaped like a large barrel, inside of which the folding protein is protected.
C) Hsp70 is most active during cell division phases.
D) Hsp70 assists in protein unfolding by hydrolyzing and remaking the protein peptide bonds.

Question

Quizplus · Accepted Answer

Hsp70 uses ATP binding and hydrolysis energy to assist in the folding of a protein. It binds to exposed hydrophobic regions of the substrate protein, preventing aggregation and facilitating proper folding. The ATP-dependent cycle of binding and release helps to drive the folding reaction. None of the other answer choices accurately describe Hsp70.

Which of the Following Statements About the Clamp-Type Chaperone Protein