Which of the following experimental procedures is most likely to speed up mRNA degradation in a eukaryotic cell?

Question

Quizplus · Accepted Answer

Removal of the 5' cap will destabilize the mRNA molecule and make it more susceptible to degradation by nucleases. Lengthening of the poly-A tail and removal of C nucleotides have no significant effect on mRNA degradation. Removal of exons can result in alternative splicing and production of different mRNA variants, but it does not necessarily lead to faster degradation.

Which of the Following Experimental Procedures Is Most Likely to Speed