A mutation in a cell results in a structural change in the signal-recognition particle (SRP)so that it does not bind to the translocation complex in the ER correctly.Which of the following processes will occur because of this mutation?

Question

Quizplus · Accepted Answer

The signal-recognition particle (SRP) is responsible for recognizing the signal sequence of proteins that are destined for the endoplasmic reticulum (ER) and targeting them to the translocation complex in the ER membrane. If there is a mutation in the SRP that prevents it from binding to the translocation complex correctly, proteins produced during translation that are destined for the ER will not be translocated into the ER. Therefore, choice B is the correct answer. The other choices are not affected by a mutation in the SRP binding to the translocation complex.

A Mutation in a Cell Results in a Structural Change