Which of the Following Mechanisms Best Describes the Manner in Which

Which of the following mechanisms best describes the manner in which lysozyme lowers the energy required for its substrate to reach its transition-state conformation?

A) by binding two molecules and orienting them in a way that favors a reaction between them
B) by altering the shape of the substrate to mimic the conformation of the transition state
C) by speeding up the rate at which water molecules collide with the substrate
D) by binding irreversibly to the substrate so that it cannot dissociate