Human beings with the inherited disease xeroderma pigmentosum have serious problems with lesions on their skin and often develop skin cancer with repeated exposure to sunlight.What type of DNA damage is not being recognized in the cells of these individuals?

Question

Quizplus · Accepted Answer

Xeroderma pigmentosum involves a deficiency in DNA nucleotide excision repair, which specifically recognizes and repairs damage caused by ultraviolet radiation. Chemical damage and X-ray irradiation damage can also be repaired by this pathway, but the deficiency in xeroderma pigmentosum only affects the recognition and repair of UV irradiation-induced damage. Mismatched bases are recognized and repaired by a different pathway called mismatch repair.

Human Beings with the Inherited Disease Xeroderma Pigmentosum Have Serious