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Rb Is a Tumor Suppressor Gene; Its Normal Function Is

Question 55

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Rb is a tumor suppressor gene; its normal function is to help restrain cell division.Loss of both copies of Rb is a causative factor in some kinds of cancer.You propose to treat these cancers by injecting the patients with a viral vector that carries a copy of the Rb gene and has the ability to infect all the cells of the body, thereby artificially driving expression of Rb in all the cells, including the cancer cells.But your colleague replies, "No! You'll kill the patient, because you will halt cell division throughout the body."
A.Why would halting cell division throughout the body kill a full-grown adult?
B.Is your colleague right in thinking that forced expression of Rb in every cell will halt all cell division?

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A.Many vital tissues in the adult body, ...

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