While Reading a Medication Package Insert, a Nurse Notes the Information

While reading a medication package insert, a nurse notes the information contained within the "black box." What is the significance of this information to the nurse? Note: Credit will be given only if all correct choices and no incorrect choices are selected. Select all that apply.

A) The drug can cause "special problems."
B) It identifies extreme adverse drug reactions.
C) It differentiates a prescribed medication from an over-the-counter medication.
D) It highlights the cost of the medication.
E) It signifies the medication is generic.