A Nurse Is Teaching a Group of Nursing Students About

A nurse is teaching a group of nursing students about the preclinical research stage of drug development. The nurse understands that the students understand the teaching by which of the following student responses? Note: Credit will be given only if all correct choices and no incorrect choices are selected. Select all that apply.

A) Most drugs do not proceed past the preclinical stage because they are found to be too toxic or just ineffective.
B) At the end of the preclinical research stage, client variability is determined and potential drug-to-drug interactions are examined.
C) The preclinical stage of research involves extensive testing on animals in the laboratory to determine if the drug will cause harm to humans.
D) Preclinical research results are always inconclusive.
E) The Food and Drug Administration (FDA) is responsible for extensive testing for safety before the pharmaceutical company can begin the preclinical research stage of development.