A person feels most comfortable wearing clothes preferred by the opposite gender, strongly wishes to be the opposite gender, and is considering a surgical procedure. The MOST likely diagnosis for this person is:

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Gender dysphoria is characterized by a strong desire to be of a different gender than one's assigned gender at birth, often accompanied by a desire to undergo surgeries and treatments to transition physically to the identified gender. This includes discomfort with one's assigned gender roles and often a preference for clothing and activities associated with the opposite gender.

A Person Feels Most Comfortable Wearing Clothes Preferred by the Opposite